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Broad Institute Unleashes Dog Genome

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An international research team led by scientists at the Broad Institute of MIT and Harvard has decoded the DNA of the domestic dog and pinpointed millions of genetic differences that distinguish dog breeds. The study also includes the first comparative analysis to encompass three distinct mammalian genomes, revealing important DNA elements common among them. Such shared genetic signatures offer crucial insights into genome organization and function, particularly in humans. Their efforts, described in the December 8 issue of Nature, shed light on the genetic similarities between dogs and humans as well as the genetic differences between dog breeds, and may guide future discoveries that improve the health of both species.

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